Androgen priming using aromatase inhibitor and hCG during early-follicular-phase GnRH antagonist down-regulation in modified antagonist protocols

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Androgen priming using aromatase inhibitor and hCG during early-follicular-phase GnRH antagonist down-regulation in modified antagonist protocols.

BACKGROUND Temporary exposure of follicles to increased levels of androgens may enhance their sensitivity to FSH. The aim of this study was to increase the intraovarian androgen level using aromatase inhibitors and hCG before controlled ovarian stimulation (COH) and to test this concept clinically. METHODS In a prospective, non-randomized study, 45 patients were treated in modified antagonist...

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Comparison of the standard GnRH antagonist protocol and the luteal phase estradiol/GnRH antagonist priming protocol in poor ovarian responders.

BACKGROUND/AIM The aim of the study was to compare the luteal estradiol patch/GnRH antagonists priming protocol (LPP) with the standard GnRH antagonist protocol in poor ovarian responders (PORs) in terms of the outcomes of in vitro fertilization (IVF) treatment. MATERIALS AND METHODS IVF outcomes of 265 cycles in 265 patients (106 in the LPP group, 159 in the standard GnRH antagonist group) w...

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art outcomes in gnrh antagonist protocol (flexible) and long gnrh agonist protocol during early follicular phase in patients with polycystic ovary syndrome: a randomized clinical trial

background: since increased lh in the early follicular phase in pcos patients especially in gnrh antagonist protocol could be associated with reduced oocyte quality and pregnancy and impared implantation. the current study was conducted to determine art outcomes in gnrh antagonist protocol (flexible) and long gnrh agonist protocol and compare them with adding gnrh antagonist in gnrh antagonist ...

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ART Outcomes in GnRH Antagonist Protocol (Flexible) and Long GnRH Agonist Protocol during Early Follicular Phase in Patients with Polycystic Ovary Syndrome: A Randomized Clinical Trial

BACKGROUND Since increased LH in the early follicular phase in PCOS patients especially in GnRH antagonist protocol could be associated with reduced oocyte quality and pregnancy and impared implantation. The current study was conducted to determine ART outcomes in GnRH antagonist protocol (flexible) and long GnRH agonist protocol and compare them with adding GnRH antagonist in GnRH antagonist (...

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GnRH agonist trigger versus hCG trigger in GnRH antagonist in IVF/ICSI cycles: A review article

Routinely, a bolus of 5.000-10.000 IU human chorionic gonadotropin (hCG) is used for the final follicular maturation and ovulation as a standard method. HCG has the same effect of luteinizing hormone (LH) with long half-life. It has the long lutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome (OHSS). Recently, gonadotropin-releasing hormone agonist (GnRH-a) trigg...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2006

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/del221